We are still waiting for the backup vendors to support vSphere 6.5.
At the moment VMware VDP 6.1.3 and Veritas Backup Exec 16 has support. Veritas Backup Exec 16 does not support vSAN 6.5 (see the Software Compatibility list here: https://www.veritas.com/support/en_US/article.000115689)
Veritas NetBackup 7.7.3 has a limited support, see here. https://www.veritas.com/support/en_US/article.000116592
Veeam B&R 9.5 Update 1 will have support and is in release candidate, this can be requested thru there support.
For a full list of Backup interoperability for vSphere 5.5, 6.0 and 60, Manfred Hofer has created a list on his blog here. http://www.vbrain.info/backup-interoperability-matrix-vsphere/ For older vSphere versions and Hyper-V, see here: http://www.vbrain.info/backup-interoperability-matrix/
Thanks to Manfred Hofer for maintaining this list.